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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNB1
All Species:
26.97
Human Site:
S370
Identified Species:
49.44
UniProt:
P14635
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14635
NP_114172.1
433
48337
S370
P
T
L
Q
H
Y
L
S
Y
T
E
E
S
L
L
Chimpanzee
Pan troglodytes
XP_517728
536
59103
S473
P
T
L
Q
H
Y
L
S
Y
T
E
E
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001091533
433
48375
S370
P
T
L
Q
H
Y
L
S
Y
T
E
E
S
L
L
Dog
Lupus familis
XP_850398
425
47378
S362
P
T
L
Q
H
Y
L
S
Y
T
E
E
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P24860
430
48033
S367
P
T
L
Q
H
Y
L
S
Y
S
E
D
S
L
L
Rat
Rattus norvegicus
P30277
423
47373
S360
P
T
L
Q
H
Y
L
S
H
T
E
E
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507609
428
47366
S365
P
L
L
Q
H
Y
L
S
Y
T
E
E
S
L
L
Chicken
Gallus gallus
P29332
399
44633
G338
T
K
Q
Q
Y
Y
T
G
Y
A
E
D
S
L
A
Frog
Xenopus laevis
P13350
397
44655
A336
P
T
L
H
H
Y
M
A
Y
S
E
E
D
L
V
Zebra Danio
Brachydanio rerio
NP_571588
398
44818
G337
P
T
L
Q
H
Y
M
G
Y
T
E
D
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20439
530
59237
R469
P
T
L
T
F
Y
S
R
Y
S
A
A
H
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39071
444
50417
R389
Q
T
L
Q
H
Y
T
R
Y
E
T
S
A
L
K
Baker's Yeast
Sacchar. cerevisiae
P24869
491
56228
G429
G
N
L
I
H
Y
S
G
G
Y
T
K
E
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.5
98.6
91.2
N.A.
86.3
84.7
N.A.
75.7
50.5
66.2
61.8
N.A.
34.3
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
99.3
94
N.A.
91.9
90.5
N.A.
84.5
66.9
78.2
75.7
N.A.
49.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
93.3
40
60
66.6
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
53.3
86.6
86.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
8
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
24
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
77
54
16
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
24
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
85
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
0
8
93
0
0
0
54
0
0
0
0
0
0
93
62
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
77
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
16
54
0
24
0
8
62
0
0
% S
% Thr:
8
77
0
8
0
0
16
0
0
54
16
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
100
0
0
85
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _